CSHL Archives Repository

Preserving and promoting the history of molecular biology.

The Repository

Contains over 380,000 online documents from Nobel laureates' James D. Watson's and Sydney Brenner's personal collections. These collections consist of correspondence, manuscripts, photographs, laboratory notebooks, administrative records, teaching files & memorabilia.

The repository and metadata were created in part, through a two-year grant funded collaboration with the Wellcome Library's Codebreakers: Makers of Modern Genetics digitization project.

Finding Aids for the majority of the 53 collections on the history of molecular biology are available on our CSHL Archives and Digital Collections websites.

The Collections

Sydney Brenner

The Sydney Brenner Collection consists of over 300 manuscript boxes of materials documenting the life and career of Dr. Sydney Brenner, co-recipient…

James D. Watson

The James D. Watson Collection consists of over 500 manuscript boxes of materials documenting the life and career of James D. Watson, co-recipient of…


Explore all 380,000+ documents of the James D. Watson and Sydney Brenner Collections using the "People & Topics" tagging system, which consists of over 14,000 tags.

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Scholars are encouraged to contact our archivists with research questions, obtaining rights to use materials or to schedule an appointment.

Letter from George Gamow to RNA club tie member

This letter from George Gamow to the RNA Tie Club includes a listing of the original club members with handwritten notation from Gamow and Watson.

(The) Kyoto Prize - Congratulations

Congratulatory letters to Sydney Brenner for being awarded the Kyoto Prize.

Moscow Biochemical Congress

Includes Watson wearing RNA tie, A.M. Liapounoff, Francis Crick, Francois Jacob, and others.

Watson and Crick at the Salk Institute

Photographs of James D. Watson and Francis Crick at the Salk Institute. One photographs is autographed by Watson and Crick. Also includes a letter…