CSHL Archives Repository

Preserving and promoting the history of molecular biology.

The Repository

Contains over 380,000 online documents from Nobel laureates' James D. Watson's and Sydney Brenner's personal collections. These collections consist of correspondence, manuscripts, photographs, laboratory notebooks, administrative records, teaching files & memorabilia.

The repository and metadata were created in part, through a two-year grant funded collaboration with the Wellcome Library's Codebreakers: Makers of Modern Genetics digitization project.

Finding Aids for the majority of the 53 collections on the history of molecular biology are available on our CSHL Archives and Digital Collections websites.

The Collections

Sydney Brenner

The Sydney Brenner Collection consists of over 300 manuscript boxes of materials documenting the life and career of Dr. Sydney Brenner, co-recipient…

James D. Watson

The James D. Watson Collection consists of over 500 manuscript boxes of materials documenting the life and career of James D. Watson, co-recipient of…


Explore all 380,000+ documents of the James D. Watson and Sydney Brenner Collections using the "People & Topics" tagging system, which consists of over 14,000 tags.

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Scholars are encouraged to contact our archivists with research questions, obtaining rights to use materials or to schedule an appointment.

The Recombinant DNA Scare Director's Report

Watson’s 1976 CSHL Director’s Report on Recombinant DNA.

Moscow Biochemical Congress

Includes Watson wearing RNA tie, A.M. Liapounoff, Francis Crick, Francois Jacob, and others.

Birthday Card - 60th

Birthday card from Leslie Orgel and others to Sydney Brenner.

Watson and Albert Szent-Gyorgyi, Cape Cod, MA

Photographic prints of Watson and Albert Szent-Gyorgyi at Szent-Gyorgyi’s home in Cape Cod, MA