CSHL Archives Repository

Preserving and promoting the history of molecular biology.

The Repository

Contains over 380,000 online documents from Nobel laureates' James D. Watson's and Sydney Brenner's personal collections. These collections consist of correspondence, manuscripts, photographs, laboratory notebooks, administrative records, teaching files & memorabilia.

The repository and metadata were created in part, through a two-year grant funded collaboration with the Wellcome Library's Codebreakers: Makers of Modern Genetics digitization project.

Finding Aids for the majority of the 53 collections on the history of molecular biology are available on our CSHL Archives and Digital Collections websites.

The Collections

James D. Watson

The James D. Watson Collection consists of over 500 manuscript boxes of materials documenting the life and career of James D. Watson, co-recipient of…

Sydney Brenner

The Sydney Brenner Collection consists of over 300 manuscript boxes of materials documenting the life and career of Dr. Sydney Brenner, co-recipient…


Explore all 380,000+ documents of the James D. Watson and Sydney Brenner Collections using the "People & Topics" tagging system, which consists of over 14,000 tags.

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Scholars are encouraged to contact our archivists with research questions, obtaining rights to use materials or to schedule an appointment.

Time Life, Inc. Portraits

Portraits of Watson in his Harvard classroom taken by Time Life, Inc. for their publication The Scientist.

Letter from George Gamow to RNA club tie member

This letter from George Gamow to the RNA Tie Club includes a listing of the original club members with handwritten notation from Gamow and Watson.

Wilkins, Maurice

Handwritten letters from Maurice Wilkins to Francis Crick.

Watson and Crick at the Salk Institute

Photographs of James D. Watson and Francis Crick at the Salk Institute. One photographs is autographed by Watson and Crick. Also includes a letter…