CSHL Archives Repository

Preserving and promoting the history of molecular biology.

The Repository

Contains over 380,000 online documents from Nobel laureates' James D. Watson's and Sydney Brenner's personal collections. These collections consist of correspondence, manuscripts, photographs, laboratory notebooks, administrative records, teaching files & memorabilia.

The repository and metadata were created in part, through a two-year grant funded collaboration with the Wellcome Library's Codebreakers: Makers of Modern Genetics digitization project.

Finding Aids for the majority of the 53 collections on the history of molecular biology are available on our CSHL Archives and Digital Collections websites.

The Collections

Sydney Brenner

The Sydney Brenner Collection consists of over 300 manuscript boxes of materials documenting the life and career of Dr. Sydney Brenner, co-recipient…

James D. Watson

The James D. Watson Collection consists of over 500 manuscript boxes of materials documenting the life and career of James D. Watson, co-recipient of…


Explore all 380,000+ documents of the James D. Watson and Sydney Brenner Collections using the "People & Topics" tagging system, which consists of over 14,000 tags.

Build your own private selections lists, tags and notes. Login/register to see this functionality.


Scholars are encouraged to contact our archivists with research questions, obtaining rights to use materials or to schedule an appointment.

RNA Tie Club (Includes George Gamow Correspondence)

Letter regarding the RNA Tie Club, sent from Ala (George Gamow) to Tyr (Francis Crick).

Wilkins, Maurice

Handwritten letters from Maurice Wilkins to Francis Crick.

Rosensteil Award - Brandeis University

Sydney Brenner, Alexander Rich & Seymour Benzer at Rosensteil Award, Brandeis University; Sydney Brenner speaks to a man at the Rosensteil Award,…

RNA Tie Club, Cambridge

Photograph of Francis Crick, Alex Rich, Leslie Orgel, and James Watson in Cambridge wearing their RNA ties